THE TABLET FORMULATIONS EFERVESEN EXTRACT OF CINNAMON BARK WITH VARIATIONS IN THE TYPE OF SWEETENER

Septia Andini, Erni Rustiani, Dwi Indriati

Abstract


Cinnamon Bark contains flavonoids, tannins, alkaloids, and phenols. Phenolic compounds contained in cinnamon is a sinamat acid is effective as anti diabetic. This research aims to determine the formula preparations tablets efervesen extract of cinnamon bark with a certain type of sweetener that favored the panelists and the levels of sinamat acid in efervesen tablets and extracts. The formula is made with different types of sweeteners such as aspartame stevia 1.5%, 3.5% and 1% sukralosa. The results of the analysis showed no difference in sweeteners influence against the parameters of color and scent but the effect on the parameters of taste every formula. Formula tablets efervesen extract of cinnamon bark that is favored by panelists based on based on the parameters of taste is formula 1 with the sweetener aspartame concentration of 1.5% and a formula 3 with sweetener sukralosa concentration 1% preferred formula panelists. The results of the analysis of the levels of sinamat acid in extract of cinnamon bark obtained the level of 471, 13 mg/g as for Formula 1 tablet efervesen acquired the levels of 369.76 mg/gram

Keywords


cinnamon bark; efervesen; sinamat acid tablets

Full Text:

PDF

References


[1] Gunawan, D., Mulyani, S.2004. Ilmu Obat Alam(Farmakognosi) Jilid I. Penebar Swadaya,Jakarta.

[2] Alfisyahrin, N. M., Moerfiah., Rustiani, E. 2013. Efektivitas Sediaan Tablet Ekstrak Kulit Kayu Manis (Cinnamomum burmanii) sebagai Antidiabetes pada Tikus Putih Jantan Galur Sprague dawley yang Diinduksi Aloksan. Skripsi. Fakultas Matematika dan Ilmu pengetahuan Alam. Universitas Pakuan : Bogor.

[3] Alfiani, N., Wardatun, S., Rustiani, E. 2017. Study Effect Type of Extraction Method and Type of Solvent to Cinnamaldehyde and Trans-Cinnamic Acid Dry Extract Cinnamon (Cinnamomum burmanii [Ness & T, Nees] Blume.). Skripsi. Fakultas Matematika dan Ilmu pengetahuan Alam. Universitas Pakuan : Bogor.

[4] Lachman, L. Lieberman, H. A. Kanig, J. L. 1994. Teori dan Praktik Farmasi Fisik Edisi III. Jakarta : UI Press.

[5] Kusumawati, Y., Rustiani, E., Almasyhuri. 2017. Pengembangan Tablet Efervesen Kombinasi Brokoli dan Pegagan dengan Kombinasi Asam dan Basa. Skripsi. Fakultas Matematika dan Ilmu pengetahuan Alam. Universitas Pakuan : Bogor.

[6] Dep.Kes. 1979. Farmakope Indonesia Edisi III. Jakarta: Departemen Kesehatan Republik Indonesia.

[7] Ansel, H.C. 2005. Pengantar Bentuk Sediaan Farmasi. Edisi IV. Alih Bahasa. Farida Ibrahim. Jakarta: UI Press.

[8] BPOM. 2014. Peraturan Kepala BPOM RI No.12 tahun 2014 tentang Persyaratan Mutu Obat tradisional. Jakarta.

[9] Aulton, E. M. 1988. Pharmaceutics Science of Dosage Form Design. London: Churcill Living Stones. Hal 247-312

[10] Fonner, D.E., Anderson, N.R., Banker, C.S., 1981. Granulation and Tablet Characteristic in Liebermen, H.A., Lachman, L., (eds) Pharmaceutical Dosage Form : Tablet, Vol.2 Mercel Dekker Inc. New York. 226-231

[11] Council of Europe. 1997. European Pharmacopoeia Third Edition. Strasbourg. Hal.1753.




DOI: https://doi.org/10.33751/jsi.v1i02.999

Refbacks

  • There are currently no refbacks.