UJI ANTIBAKTERI SEDIAAN OBAT KUMUR EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) TERHADAP Streptococcus mutans
Abstract
Pandanus amaryllifolius Roxb leaf has potential as an antibacterial. The research aims to know the ability of stocks to mouthwash scented pandan leaf extract inhibits Streptococcus mutans and in determining the fragrant pandanus phytochemicals compounds. Wide-Area Drag testing (LDH) mouthwash extracts was performed with a concentration of 15%, 17.5% and 20%. Test the phytochemical saponins, alkaloids, tannins and flavonoids qualitatively on 0.5 g powder. Testing stabilita include organoleptik observations of color, aroma, taste preparation, test the pH, specific gravity and viscosity. The results showed that the material of pandanus leaf extract mouthwash scented antibacterial nature against Streptococcus mutans with a concentration of extracts of 15%, 17.5% and 20% showed values of LDH consecutive 16.3 mm; 22.6 mm and 28.3 mm earlier in the week while in week 8 loss to the value of LDH is 12.5 mm; 15.5 mm; and 19.6 mm. The active compounds in the leaves of pandanus is alkaloids, saponins, tannins and flavonoids. Mouthwashes stored at 25-30 ° C for 8 weeks are relatively stable for color, flavor, taste, pH, specific gravity, and viscosity, compared to a temperature of 40oC.
Key words: Pandan fragrance, Streptococcus mutans, mouthwash
References
Akinjogunla OJ, Yah CS, Eghafona NO and Ogbemudia FO. 2010. Antibacterial activity of leave extracts of Nymphaea lotus (Nymphaeaceae) on Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin resistant Staphylococcus aureus (VRSA) isolated from clinical samples. Annuals of Biological Research 1 (2), 174-184.
Dalimartha S. 2000. Atlas Tumbuhan Obat Indonesia. Jilid I. Jakarta:Trubus Agriwidya,
DepKes RI. 1979. Farmakope Indonesia. Jilid III. Direktorat Jenderal Pengawasan Obat dan Makanan, Jakarta.
__________. 1985. Materia Medika Indonesia. Jilid V. Direktorat Jenderal Pengawasan Obat dan Makanan, Jakarta.
__________. 2000. Penetapan Kadar Air. Direktorat Jenderal Pengawasan Obat dan Makanan, Jakarta.
Dumaoal, OSR, Alaras, LB, Dahilan KG, Sarah, Depadua AA, Pulmones, CJG. 2010. In Vitro Activity of Pandan (Pandanus amaryllifolius) Leaves Crude Extract Against Selected Bacterial Isolates. National Peer Reviewed Journal. Vol 4:102-124. Doi:http://dx.doi.org/10.7719/ jpair. v4i1.103.
Emelia Dwita. 2014. Efek Antibakteri Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Terhadap Pertumbuhan Aggregati bacter Actinomycetemcomitans Secara in Vitro. Fakultas Kedokteran Gigi Universitas Syiah Kuala. Etd.unsyiah.ac.id/index.phpp =show_detail&id=5604.
Galeotti F, Barile E, Curir P, Dolci M and Lanzotti V. 2008. Flavonoids from carnation (Dianthus caryophyllus) and their antifungal activity. Phytochemistry Letters 1, pp. 44.
Karpinski TM and Szkaradkiewicz AK. 2013. Microbiology of Dental Caries. Jbiol Earth Sci. 3 (1), M21-M24.
Martin A. 1993. Farmasi Fisika Dasar-Dasar Kimia Fisik Dalam Ilmu Farmaseutik Edisi ke-2. Jilid III. Jakarta: UI Press.
Martindale. 1996. The Extra Pharmacopeia. Thirty-first Edition. Edited byJames E. R. Raynolds. London: Royal Pharmaceutical Society.
Robinson T. 1995. Kandungan Organik Tumbuhan Tinggi Edisi IV, (Padmawi-nata, Penerjemah). Bandung : ITB Press.
Roeslan BO. 1996. Karakteristik Streptococcus mutans Penyebab Karies Gigi. Majalah Ilmiah Kedokteran Gigi Usakti, 10, 112-113.
Setiorini HE. 2011. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Pandan Wangi (Pandanus ammaryllifolius Roxb.) Terhadap Propionibacterium acnes DAN Pseudomonas aeruginosa Serta Skrining Fitokimia. Skripsi. Universitas Muhammadiyah Surakarta.
Syamsuhidayat SS, Hutapea JR. 1994. Inventaris Tanaman Obat Indonesia Jilid I. DepKes RI. Jakarta.
Rajendra CE, Magadum GS, Nadaf MA, Yashoda SV and Manjula M. 2011. Phytochemical Screening of the Rhizoma of Kaemferia Galanga. Int. J. Pharmacognosy and Phyto- chemical Research 3 (3), 61-63.
Tranggono. 1992. Penilaian Organoleptik. Jakarta : Angkasa Bhatara Karya.
Zamora-Ros R, Agudo A, Luján-Barroso L, Romieu I, Ferrari P and Knaze V. 2012. Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. American Journal of Clinical Nutrition, 96 (6), pp. 1398–1408.DOI: 10.33751/ekol.v17i1.832
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.